Contrave (Naltrexone/Bupropion)

Weight Loss

What is Contrave?

Contrave contains a combination of bupropion and naltrexone. Bupropion is an antidepressant medicine that can alsodecrease appetite. Naltrexone is usually given to block the effects of opioids or alcohol in people with addiction problems. Naltrexone may also curb hunger and food cravings.

Contrave is an anorexiant and is used to help manage weight in obese and overweight adults with weight-related medical problems. This medicine is used together with diet and exercise.


Put food in its place, Get Control over Cravings

CONTRAVE is an FDA-approved weight-loss medication for people who are overweight or struggling with obesity. It is uniquely designed to reduce hunger and control cravings, so you can lose weight and keep it off.

When You Eat for Comfort

When it comes to creating a weight-loss plan, one size doesn’t fit all. Everyone faces different challenges that keep them from weight-loss success. For some, it is difficult to control cravings when dealing with emotions like stress. If this sounds familiar, adding CONTRAVE to diet and exercise may help you lose weight and keep it off.

CONTRAVE targets 2 areas of the brain
that cause hunger and cravings

Hunger happens when your brain tells you that it needs nutrition and that any food will satisfy this need. 

Cravings happen when your brain wants specific foods, even though you may not feel hungry.

Contrave Side Effects

The most common side effects of CONTRAVE include nausea, constipation, headache, vomiting, dizziness, trouble sleeping, dry mouth, and diarrhea. These are not all of the possible side effects of CONTRAVE.

Contrave FAQs

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Do not take more than 4 tablets in 1 day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of this medicine can be fatal, especially if you also take an opioid medicine.

What to avoid

Drinking alcohol with bupropion may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can also cause seizures in a regular drinker who suddenly stops drinking.